| 1. Ronde | 12.02.2022 | Vitória Guimarães [A-jun] | - | FC Alverca [A-jun] | 2:2 | ||||
| 2. Ronde | 19.02.2022 | Sporting Braga [A-jun] | - | Vitória Guimarães [A-jun] | 3:0 | ||||
| 3. Ronde | 26.02.2022 | Vitória Guimarães [A-jun] | - | FC Porto [A-jun] | 1:2 | ||||
| 7. Ronde | 09.04.2022 | Rio Ave FC [A-jun] | - | Vitória Guimarães [A-jun] | 3:3 |  |
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| 9. Ronde | 23.04.2022 | Vitória Guimarães [A-jun] | - | Sporting Braga [A-jun] | 0:1 | ||||
| 10. Ronde | 30.04.2022 | FC Porto [A-jun] | - | Vitória Guimarães [A-jun] | 2:1 | ||||
| 11. Ronde | 07.05.2022 | Vitória Guimarães [A-jun] | - | SL Benfica [A-jun] | 0:2 | ||||
| 13. Ronde | 21.05.2022 | GD Estoril [A-jun] | - | Vitória Guimarães [A-jun] | 0:4 |
Portugal