| 2. Ronde | 15.01.2022 | Deportivo Toluca [] | - | Club Necaxa [] | 2:1 | ||||
| 3. Ronde | 22.01.2022 | Club Necaxa [] | - | Cruz Azul [] | 4:1 | ||||
| 4. Ronde | 29.01.2022 | FC Juárez [] | - | Club Necaxa [] | 1:0 |  |
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| 14. Ronde | 09.04.2022 | CF Pachuca [] | - | Club Necaxa [] | 0:1 | ||||
| 18. Ronde | 07.05.2022 | Cruz Azul [] | - | Club Necaxa [] | 1:3 |
Mexico