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| 04.12.2010 | 12:00 | Lokomotiv Plovdiv | - | Minyor Pernik | 2:1 (0:0) | |
| 12:00 | Pirin Blagoevgrad | - | PFC Kaliakra Kavarna | 3:1 (0:1, 1:1) n.v. | ||
| 12:00 | FK Dobrudzha | - | PSFC Chernomorets | 0:3 (0:2) | ||
| 12:00 | Etar Veliko Tarnovo | - | Slavia Sofia | 0:1 (0:1) | ||
| 12:00 | Kom-Minyor | - | Cherno More Varna | 0:1 (0:0) | ||
| 12:00 | PFC Chernomorets Pomorie | - | PFC Litex Lovech | 0:2 (0:1) | ||
| 08.12.2010 | 15:00 | Levski Sofia | - | PFC Beroe | 1:0 (0:0) | |
| 11.12.2010 | 12:00 | FK Malesh Mikrevo | - | CSKA Sofia | 0:3 (0:0) |
