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| 09.04.2021 | 16:00 | Vysočina Jihlava | - | FK Fotbal Třinec | 1:0 (0:0) | |
| 10.04.2021 | 13:00 | MFK Chrudim | - | FK Ústí nad Labem | 0:1 (0:1) | |
| 16:30 | FK Dukla Praha | - | FK Varnsdorf | 1:2 (0:2) | ||
| 16:30 | Slavoj Vyšehrad | - | FC Hradec Králové | 1:4 (0:2) | ||
| 11.04.2021 | 10:15 | Viktoria Žižkov | - | FK Blansko | 1:1 (0:1) | |
| 16:30 | FK MAS Táborsko | - | 1. SK Prostějov | 1:2 (0:1) | ||
| 16:30 | FC Sellier & Bellot Vlašim | - | SK Líšeň | 2:1 (1:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Hradec Králové | 17 | 11 | 4 | 2 | 35:16 | 19 | 37 |
| 2 |
|
1. SK Prostějov | 17 | 9 | 5 | 3 | 29:21 | 8 | 32 |
| 3 |
|
SK Líšeň | 17 | 8 | 7 | 2 | 27:18 | 9 | 31 |
| 4 |
|
FK Ústí nad Labem | 17 | 8 | 5 | 4 | 18:20 | -2 | 29 |
| 5 |
|
MFK Chrudim | 17 | 8 | 3 | 6 | 25:15 | 10 | 27 |
| 6 |
|
FC Sellier & Bellot Vlašim | 17 | 8 | 3 | 6 | 27:20 | 7 | 27 |
| 7 |
|
FK Dukla Praha | 17 | 6 | 6 | 5 | 27:19 | 8 | 24 |
| 8 |
|
Viktoria Žižkov | 17 | 7 | 2 | 8 | 25:27 | -2 | 23 |
| 9 |
|
FK Varnsdorf | 17 | 5 | 7 | 5 | 15:20 | -5 | 22 |
| 10 |
|
Vysočina Jihlava | 17 | 5 | 4 | 8 | 23:29 | -6 | 19 |
| 11 |
|
FK Blansko | 17 | 4 | 5 | 8 | 19:22 | -3 | 17 |
| 12 |
|
FK Fotbal Třinec | 17 | 4 | 5 | 8 | 20:27 | -7 | 17 |
| 13 |
|
FK MAS Táborsko | 17 | 4 | 4 | 9 | 16:19 | -3 | 16 |
| 14 |
|
Slavoj Vyšehrad | 17 | 1 | 2 | 14 | 9:42 | -33 | 5 |
| Promotie | |
| Degradatie |
