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| 01.05.2022 | 15:00 | AS Monaco | - | Castelnau Le Crès FC | 1:0 (0:0) | |
| 15:00 | SC Air Bel | - | Gazélec FC Ajaccio | 3:4 (0:0) | ||
| 15:00 | Clermont Foot 63 | - | Andrézieux-Bouthéon FC | 3:2 (2:2) | ||
| 15:00 | OGC Nice | - | Olympique Marseille | 0:1 (0:0) | ||
| 15:00 | AS Saint-Priest | - | Olympique de Valence | 4:3 (3:0) | ||
| 15:00 | AS Saint-Étienne | - | AC Ajaccio | 2:1 (2:0) | ||
| 15:30 | Lyon-La Duchère | - | Racing FC Toulon | 3:3 (2:1) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
AC Ajaccio | 25 | 16 | 5 | 4 | 48:19 | 29 | 53 |
| 2 |
|
AS Saint-Étienne | 25 | 17 | 2 | 6 | 47:25 | 22 | 53 |
| 3 |
|
Olympique Marseille | 25 | 15 | 5 | 5 | 61:28 | 33 | 50 |
| 4 |
|
AS Saint-Priest | 25 | 14 | 2 | 9 | 50:38 | 12 | 44 |
| 5 |
|
AS Monaco | 25 | 12 | 3 | 10 | 45:38 | 7 | 39 |
| 6 |
|
Clermont Foot 63 | 25 | 12 | 2 | 11 | 46:39 | 7 | 38 |
| 7 |
|
Lyon-La Duchère | 25 | 11 | 4 | 10 | 47:63 | -16 | 37 |
| 8 |
|
Olympique de Valence | 25 | 12 | 0 | 13 | 46:43 | 3 | 36 |
| 9 |
|
OGC Nice | 25 | 10 | 6 | 9 | 42:43 | -1 | 36 |
| 10 |
|
Castelnau Le Crès FC | 25 | 10 | 5 | 10 | 40:36 | 4 | 35 |
| 11 |
|
Gazélec FC Ajaccio | 25 | 8 | 4 | 13 | 34:53 | -19 | 28 |
| 12 |
|
Andrézieux-Bouthéon FC | 25 | 6 | 3 | 16 | 32:58 | -26 | 21 |
| 13 |
|
Racing FC Toulon | 25 | 2 | 9 | 14 | 22:53 | -31 | 15 |
| 14 |
|
SC Air Bel | 25 | 3 | 4 | 18 | 27:51 | -24 | 13 |
| Degradatie |
