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| 12.03.2022 | 16:00 | SM Caen B | - | FC Lorient B | 1:3 (0:2) | |
| 16:00 | FC Versailles | - | Vannes OC | 1:0 (0:0) | ||
| 17:00 | Stade Plabennec | - | C'Chartres Football | 3:0 (1:0) | ||
| 18:00 | AS Vitré | - | US Granvillaise | 1:1 (1:1) | ||
| 18:00 | Blois Foot 41 | - | EA Guingamp B | 5:2 (2:1) | ||
| 18:00 | FC Rouen 1899 | - | SO Romorantin | 2:1 (1:0) | ||
| 18:00 | St-Pryvé St-Hilaire | - | AS Poissy | 2:3 (0:0) | ||
| 18:00 | US Saint-Malo | - | Châteaubriant Voltigeurs | 3:2 (2:1) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Versailles | 21 | 12 | 8 | 1 | 32:12 | 20 | 44 |
| 2 |
|
FC Lorient B | 21 | 11 | 5 | 5 | 29:16 | 13 | 38 |
| 3 |
|
C'Chartres Football | 21 | 11 | 3 | 7 | 35:26 | 9 | 36 |
| 4 |
|
Blois Foot 41 | 21 | 10 | 6 | 5 | 34:33 | 1 | 36 |
| 5 |
|
Vannes OC | 21 | 9 | 6 | 6 | 31:24 | 7 | 33 |
| 6 |
|
St-Pryvé St-Hilaire | 21 | 9 | 5 | 7 | 27:23 | 4 | 32 |
| 7 |
|
SM Caen B | 21 | 8 | 6 | 7 | 24:27 | -3 | 30 |
| 8 |
|
Châteaubriant Voltigeurs | 21 | 8 | 4 | 9 | 25:27 | -2 | 28 |
| 9 |
|
FC Rouen 1899 | 21 | 6 | 8 | 7 | 21:21 | 0 | 26 |
| 10 |
|
AS Poissy | 21 | 5 | 10 | 6 | 24:26 | -2 | 25 |
| 11 |
|
EA Guingamp B | 21 | 6 | 7 | 8 | 25:34 | -9 | 25 |
| 12 |
|
US Granvillaise | 21 | 4 | 12 | 5 | 20:20 | 0 | 24 |
| 13 |
|
US Saint-Malo | 21 | 6 | 5 | 10 | 17:25 | -8 | 23 |
| 14 |
|
SO Romorantin | 21 | 5 | 4 | 12 | 18:32 | -14 | 19 |
| 15 |
|
AS Vitré | 21 | 4 | 6 | 11 | 22:30 | -8 | 18 |
| 16 |
|
Stade Plabennec | 21 | 4 | 5 | 12 | 20:28 | -8 | 17 |
| Promotie | |
| Degradatie |
