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| 19.02.2022 | 16:00 | AS Monaco (CFA) | - | Lyon-La Duchère | 2:2 (1:0) | |
| 16:00 | Étoile FC | - | Olympique Lyon (CFA) | 2:0 (1:0) | ||
| 17:00 | GFA Rumilly Vallières | - | Louhans-Cuiseaux | 0:3 (0:1) | ||
| 17:00 | GOAL FC | - | Marignane Gignac FC | 1:0 (0:0) | ||
| 17:00 | SC Toulon | - | Jura Sud | 2:1 (1:1) | ||
| 18:00 | Aubagne FC | - | Olympique Marseille (CFA) | 1:2 (1:1) | ||
| 18:00 | FC Martigues | - | Hyères FC | 3:1 (1:1) | ||
| 18:00 | AS Saint-Priest | - | RC Grasse | 3:3 (3:1) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
GOAL FC | 19 | 12 | 5 | 2 | 36:13 | 23 | 41 |
| 2 |
|
FC Martigues | 19 | 9 | 7 | 3 | 24:16 | 8 | 34 |
| 3 |
|
Louhans-Cuiseaux | 19 | 8 | 7 | 4 | 25:17 | 8 | 31 |
| 4 |
|
RC Grasse | 19 | 8 | 7 | 4 | 21:17 | 4 | 31 |
| 5 |
|
Aubagne FC | 19 | 8 | 6 | 5 | 25:19 | 6 | 30 |
| 6 |
|
Marignane Gignac FC | 19 | 8 | 4 | 7 | 20:17 | 3 | 28 |
| 7 |
|
Olympique Lyon (CFA) | 19 | 7 | 7 | 5 | 20:20 | 0 | 28 |
| 8 |
|
Jura Sud | 19 | 7 | 5 | 7 | 24:26 | -2 | 26 |
| 9 |
|
Étoile FC | 19 | 6 | 7 | 6 | 18:16 | 2 | 25 |
| 10 |
|
Lyon-La Duchère | 19 | 5 | 7 | 7 | 20:23 | -3 | 22 |
| 11 |
|
SC Toulon | 19 | 4 | 9 | 6 | 15:17 | -2 | 21 |
| 12 |
|
AS Monaco (CFA) | 19 | 5 | 6 | 8 | 19:25 | -6 | 21 |
| 13 |
|
Hyères FC | 19 | 4 | 8 | 7 | 19:23 | -4 | 20 |
| 14 |
|
GFA Rumilly Vallières | 19 | 4 | 6 | 9 | 14:25 | -11 | 18 |
| 15 |
|
AS Saint-Priest | 19 | 4 | 4 | 11 | 21:30 | -9 | 16 |
| 16 |
|
Olympique Marseille (CFA) | 19 | 4 | 3 | 12 | 16:33 | -17 | 15 |
| Promotie | |
| Degradatie |
