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| 09.10.2021 | 16:00 | Olympique Lyon (CFA) | - | Olympique Marseille (CFA) | 2:2 (0:1) | |
| 17:00 | AS Monaco (CFA) | - | AS Saint-Priest | 4:2 (2:0) | ||
| 17:00 | Hyères FC | - | GOAL FC | 1:1 (0:0) | ||
| 18:00 | FC Martigues | - | GFA Rumilly Vallières | 3:1 (2:0) | ||
| 18:00 | RC Grasse | - | Jura Sud | 1:4 (0:2) | ||
| 18:00 | Louhans-Cuiseaux | - | Aubagne FC | 3:2 (2:0) | ||
| 18:00 | Lyon-La Duchère | - | Étoile FC | 0:1 (0:1) | ||
| 18:00 | Marignane Gignac FC | - | SC Toulon | 0:1 (0:1) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Louhans-Cuiseaux | 9 | 5 | 3 | 1 | 14:7 | 7 | 18 |
| 2 |
|
GOAL FC | 9 | 5 | 2 | 2 | 13:7 | 6 | 17 |
| 3 |
|
RC Grasse | 9 | 5 | 2 | 2 | 10:7 | 3 | 17 |
| 4 |
|
Aubagne FC | 9 | 5 | 1 | 3 | 14:12 | 2 | 16 |
| 5 |
|
Olympique Lyon (CFA) | 9 | 4 | 3 | 2 | 14:10 | 4 | 15 |
| 6 |
|
Jura Sud | 9 | 4 | 2 | 3 | 12:8 | 4 | 14 |
| 7 |
|
FC Martigues | 9 | 3 | 4 | 2 | 8:9 | -1 | 13 |
| 8 |
|
SC Toulon | 9 | 3 | 4 | 2 | 9:7 | 2 | 13 |
| 9 |
|
AS Monaco (CFA) | 9 | 4 | 1 | 4 | 11:10 | 1 | 13 |
| 10 |
|
Lyon-La Duchère | 9 | 3 | 2 | 4 | 8:8 | 0 | 11 |
| 11 |
|
GFA Rumilly Vallières | 9 | 3 | 2 | 4 | 9:11 | -2 | 11 |
| 12 |
|
Hyères FC | 9 | 2 | 4 | 3 | 5:7 | -2 | 10 |
| 13 |
|
Étoile FC | 9 | 2 | 3 | 4 | 7:11 | -4 | 9 |
| 14 |
|
Marignane Gignac FC | 9 | 2 | 2 | 5 | 6:12 | -6 | 8 |
| 15 |
|
Olympique Marseille (CFA) | 9 | 2 | 1 | 6 | 8:15 | -7 | 7 |
| 16 |
|
AS Saint-Priest | 9 | 2 | 0 | 7 | 9:16 | -7 | 6 |
| Promotie | |
| Degradatie |
