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| 11.09.2021 | 17:00 | FC Chamalières | - | FC Nantes (CFA) | 2:2 (0:0) | |
| 18:00 | Andrézieux-Bouthéon FC | - | US Colomiers | 0:1 (0:0) | ||
| 18:00 | Bourges Foot 18 | - | AS Béziers | 0:1 (0:0) | ||
| 18:00 | Bergerac Foot | - | Stade Montois | 3:0 (3:0) | ||
| 18:00 | Montpellier HSC (CFA) | - | Canet Roussillon | 0:0 (0:0) | ||
| 18:00 | Le Puy Foot 43 | - | Moulins Yzeure Foot | 0:0 (0:0) | ||
| 18:00 | Angers SCO II | - | Trélissac FC | 0:1 (0:0) | ||
| 18:00 | Vendée Les Herbiers | - | Angoulême CFC | 1:2 (0:1) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Angoulême CFC | 6 | 4 | 1 | 1 | 9:3 | 6 | 13 |
| 2 |
|
Andrézieux-Bouthéon FC | 6 | 4 | 0 | 2 | 10:6 | 4 | 12 |
| 3 |
|
Moulins Yzeure Foot | 6 | 3 | 3 | 0 | 5:1 | 4 | 12 |
| 4 |
|
US Colomiers | 6 | 3 | 2 | 1 | 7:4 | 3 | 11 |
| 5 |
|
Le Puy Foot 43 | 6 | 3 | 2 | 1 | 5:2 | 3 | 11 |
| 6 |
|
AS Béziers | 6 | 3 | 2 | 1 | 6:4 | 2 | 11 |
| 7 |
|
Bergerac Foot | 6 | 3 | 1 | 2 | 9:5 | 4 | 10 |
| 8 |
|
FC Nantes (CFA) | 6 | 2 | 3 | 1 | 9:8 | 1 | 9 |
| 9 |
|
Vendée Les Herbiers | 6 | 2 | 2 | 2 | 10:10 | 0 | 8 |
| 10 |
|
Trélissac FC | 6 | 2 | 0 | 4 | 4:8 | -4 | 6 |
| 11 |
|
Bourges Foot 18 | 6 | 1 | 2 | 3 | 3:4 | -1 | 5 |
| 12 |
|
FC Chamalières | 6 | 1 | 2 | 3 | 6:10 | -4 | 5 |
| 13 |
|
Angers SCO II | 6 | 1 | 2 | 3 | 4:9 | -5 | 5 |
| 14 |
|
Montpellier HSC (CFA) | 6 | 0 | 2 | 4 | 3:7 | -4 | 2 |
| 15 |
|
Canet Roussillon | 6 | 3 | 2 | 1 | 7:6 | 1 | 0 |
| 16 |
|
Stade Montois | 6 | 0 | 0 | 6 | 6:16 | -10 | 0 |
| Promotie | |
| Degradatie |
