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| 21.12.2010 | 14:30 | Olympiakos Volou | - | Panserraikos | 2:0 (0:0) | |
| 16:30 | Atromitos | - | AO Kavala | 1:0 (0:0) | ||
| 22.12.2010 | 14:30 | PAOK Saloniki | - | PAS Giannina | 2:1 (2:0) | |
| 16:30 | Asteras Tripolis | - | Olympiakos | 0:1 (0:0) | ||
| 19:00 | Panathinaikos | - | AO Trikala | 3:2 (2:1) | ||
| 23.12.2010 | 14:30 | Ethnikos Asteras | - | Diagoras FC | 1:1 (0:0) | |
| 16:30 | Iraklis Saloniki | - | AO Kerkyra | 1:1 (0:0) | ||
| 19:00 | AE Lárissa | - | AEK Athene | 0:4 (0:1) | ||
| Beslissingswedstrijden | ||||||
|---|---|---|---|---|---|---|
| 12.01.2011 | 14:00 | Diagoras FC | - | Ethnikos Asteras | 1:0 (1:0) | |
| 16:30 | AO Kerkyra | - | Iraklis Saloniki | 5:3 (0:0, 0:0, 0:0) d.p. | ||
