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| U | FC Voluntari | - | Argeș Pitești | 2:0 (2:0) | ||
| R | Argeș Pitești | - | FC Voluntari | 0:1 (0:0) | ||
| U: 19.04.2022 19:00 | R: 11.05.2022 18:30 | Winnaars: FC Voluntari | ||||
| U | Sepsi OSK | - | CS Universitatea Craiova | 2:1 (1:0) | ||
| R | CS Universitatea Craiova | - | Sepsi OSK | 0:1 (0:0) | ||
| U: 20.04.2022 18:30 | R: 12.05.2022 18:30 | Winnaars: Sepsi OSK | ||||
