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| U | SS Pennarossa | - | SS Murata | 1:1 (0:0) | ||
| R | SS Murata | - | SS Pennarossa | 1:2 (1:1) | ||
| U: 03.05.2022 20:45 | R: 07.05.2022 15:00 | Winnaars: SS Pennarossa | ||||
| U | SC Faetano | - | SS San Giovanni | 1:1 (0:1) | ||
| R | SS San Giovanni | - | SC Faetano | 1:2 (0:0) | ||
| U: 03.05.2022 20:45 | R: 07.05.2022 15:00 | Winnaars: SC Faetano | ||||
| U | AC Libertas | - | FC Domagnano | 5:0 (1:0) | ||
| R | FC Domagnano | - | AC Libertas | 0:3 (0:1) | ||
| U: 03.05.2022 20:45 | R: 07.05.2022 15:00 | Winnaars: AC Libertas | ||||
| U | SS Folgore/Falciano | - | FC Fiorentino | 0:2 (0:1) | ||
| R | FC Fiorentino | - | SS Folgore/Falciano | 1:2 (1:1) | ||
| U: 03.05.2022 20:45 | R: 07.05.2022 15:00 | Winnaars: FC Fiorentino | ||||
