| 5. Ronde | 03.10.2021 | CD Toledo | - | CD Marchamalo | 3:2 | ||||
| 18. Ronde | 23.01.2022 | CD Toledo | - | UD Melilla | 2:0 | ||||
| 19. Ronde | 30.01.2022 | Águilas FC | - | CD Toledo | 1:3 | ||||
| 20. Ronde | 06.02.2022 | CD Toledo | - | Atlético Mancha Real | 1:2 | ||||
| 21. Ronde | 13.02.2022 | CS Puertollano CF | - | CD Toledo | 2:1 | ||||
| 22. Ronde | 20.02.2022 | CD Marchamalo | - | CD Toledo | 0:2 | ||||
| 23. Ronde | 27.02.2022 | CD Toledo | - | Recreativo Granada | 0:0 | ||||
| 24. Ronde | 06.03.2022 | CF Intercity | - | CD Toledo | 0:0 | ||||
| 25. Ronde | 13.03.2022 | CD Toledo | - | Mar Menor CF | 1:2 |  |
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| 27. Ronde | 27.03.2022 | CD Toledo | - | UD Socuéllamos | 0:0 |  |
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| 28. Ronde | 03.04.2022 | CA Pulpileño | - | CD Toledo | 0:0 | ||||
| 29. Ronde | 10.04.2022 | CD Toledo | - | Levante UD B | 2:2 | ||||
| 30. Ronde | 17.04.2022 | CD El Ejido 2012 | - | CD Toledo | 1:2 | ||||
| 31. Ronde | 24.04.2022 | CD Toledo | - | CF La Nucía | 0:1 | ||||
| 32. Ronde | 01.05.2022 | CD Eldense | - | CD Toledo | 3:1 | ||||
| 33. Ronde | 08.05.2022 | CD Toledo | - | Hércules CF | 1:1 | ||||
| 34. Ronde | 15.05.2022 | Real Murcia | - | CD Toledo | 2:0 |
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