| 1. Ronde | 18.10.2020 | Real Oviedo B | - | UP Langreo | 0:1 | ||||
| 2. Ronde | 25.10.2020 | UP Langreo | - | Real Valladolid B | 2:1 | ||||
| 4. Ronde | 08.11.2020 | UP Langreo | - | Sporting Gijón B | 1:1 | ||||
| 3. Ronde | 14.11.2020 | Burgos CF | - | UP Langreo | 0:2 | ||||
| 6. Ronde | 29.11.2020 | Marino de Luanco | - | UP Langreo | 1:0 | ||||
| 7. Ronde | 06.12.2020 | UP Langreo | - | Cultural Leonesa | 2:2 | ||||
| 8. Ronde | 12.12.2020 | CD Numancia | - | UP Langreo | 1:0 | ||||
| 5. Ronde | 19.12.2020 | UP Langreo | - | CD Covadonga | 3:2 | ||||
| 9. Ronde | 10.01.2021 | UP Langreo | - | CD Lealtad | 0:0 | ||||
| 10. Ronde | 17.01.2021 | UP Langreo | - | Real Oviedo B | 2:2 | ||||
| 11. Ronde | 23.01.2021 | Real Valladolid B | - | UP Langreo | 1:1 | ||||
| 12. Ronde | 31.01.2021 | UP Langreo | - | Burgos CF | 1:2 | ||||
| 13. Ronde | 07.02.2021 | Sporting Gijón B | - | UP Langreo | 2:1 | ||||
| 14. Ronde | 14.02.2021 | CD Covadonga | - | UP Langreo | 0:1 | ||||
| 15. Ronde | 21.02.2021 | UP Langreo | - | Marino de Luanco | 1:1 | ||||
| 16. Ronde | 06.03.2021 | Cultural Leonesa | - | UP Langreo | 3:1 | ||||
| 17. Ronde | 13.03.2021 | UP Langreo | - | CD Numancia | 1:1 | ||||
| 18. Ronde | 21.03.2021 | CD Lealtad | - | UP Langreo | 0:1 |
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