| 9. Ronde | 18.09.2021 | Club Tijuana [U16] | - | Pumas UNAM [U16] | 1:0 | ||||
| 11. Ronde | 02.10.2021 | Deportivo Toluca [U16] | - | Club Tijuana [U16] | 2:0 | ||||
| 15. Ronde | 30.10.2021 | Club Tijuana [U16] | - | Gallos Blancos [U16] | 3:2 | ||||
| 16. Ronde | 06.11.2021 | FC Juárez [U16] | - | Club Tijuana [U16] | 1:3 | ||||
| 17. Ronde | 13.11.2021 | Pumas UNAM [U16] | - | Club Tijuana [U16] | 0:0 | ||||
| 18. Ronde | 20.11.2021 | Club Tijuana [U16] | - | Cruz Azul [U16] | 0:0 |
Mexico