| 2. Ronde | 12.09.2021 | Real Sociedad C | - | Sestao River | 1:0 |  |
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| 16. Ronde | 16.01.2022 | Sestao River | - | CD Izarra | 0:0 | ||||
| 23. Ronde | 27.02.2022 | Sestao River | - | Racing Rioja CF | 2:0 | ||||
| 24. Ronde | 05.03.2022 | CF Ardoi | - | Sestao River | 0:2 | ||||
| 31. Ronde | 24.04.2022 | UD Logroñés Promesas | - | Sestao River | 1:1 | ||||
| 32. Ronde | 30.04.2022 | Sestao River | - | UD Mutilvera | 3:0 | ||||
| 34. Ronde | 15.05.2022 | Sestao River | - | CD Tropezón | 4:2 |
Spanje