| 4. Ronde | 09.03.2022 | Puerto Montt | - | Deportes Iquique | 0:0 |  |
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| 5. Ronde | 16.03.2022 | Deportes Iquique | - | CD Magallanes | 1:1 | |
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| 6. Ronde | 22.03.2022 | Santiago Morning | - | Deportes Iquique | 1:0 | ||||
| 8. Ronde | 09.04.2022 | Fernández Vial | - | Deportes Iquique | 0:0 | ||||
| 9. Ronde | 17.04.2022 | Deportes Iquique | - | Cobreloa | 2:0 | ||||
| 10. Ronde | 20.04.2022 | Deportes Copiapó | - | Deportes Iquique | 1:0 | ||||
| 11. Ronde | 24.04.2022 | Deportes Iquique | - | Rangers | 0:2 | ||||
| 12. Ronde | 30.04.2022 | Universidad de Concepción | - | Deportes Iquique | 2:2 | ||||
| 13. Ronde | 07.05.2022 | Deportes Iquique | - | San Luis | 1:1 | ||||
| 14. Ronde | 11.05.2022 | Barnechea | - | Deportes Iquique | 6:2 | ||||
| 15. Ronde | 15.05.2022 | Deportes Iquique | - | Recoleta | 2:1 | ||||
| 16. Ronde | 21.05.2022 | Unión San Felipe | - | Deportes Iquique | 2:0 | |
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| 17. Ronde | 29.05.2022 | Deportes Iquique | - | Deportes Melipilla | 3:0 | ||||
| 26. Ronde | 31.08.2022 | Cobreloa | - | Deportes Iquique | 2:1 | ||||
| 32. Ronde | 16.10.2022 | Recoleta | - | Deportes Iquique | 3:0 | ||||
| 33. Ronde | 22.10.2022 | Deportes Iquique | - | Unión San Felipe | 3:0 | |
Chili