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| 30.04.2022 | 00:00 | Unión San Felipe | - | Cobreloa | 1:1 (0:1) | |
| 00:00 | Melipilla | - | Barnechea | 2:1 (1:1) | ||
| 02:30 | Universidad de Concepción | - | Deportes Iquique | 2:2 (0:0) | ||
| 02:30 | San Luis | - | Deportes Temuco | 1:1 (1:0) | ||
| 20:30 | Puerto Montt | - | Santa Cruz | 3:0 (1:0) | ||
| 20:30 | Copiapó | - | Fernández Vial | 4:0 (2:0) | ||
| 23:00 | Rangers | - | Santiago Morning | 2:3 (1:2) | ||
| 01.05.2022 | 01:30 | Recoleta | - | Santiago Wanderers | 1:2 (0:1) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CD Magallanes | 11 | 10 | 1 | 0 | 25:8 | 17 | 31 |
| 2 |
|
Cobreloa | 12 | 8 | 2 | 2 | 19:10 | 9 | 26 |
| 3 |
|
Unión San Felipe | 11 | 7 | 4 | 0 | 12:3 | 9 | 25 |
| 4 |
|
Rangers | 12 | 7 | 1 | 4 | 20:15 | 5 | 22 |
| 5 |
|
Santiago Morning | 11 | 4 | 5 | 2 | 17:15 | 2 | 17 |
| 6 |
|
Puerto Montt | 12 | 3 | 6 | 3 | 14:12 | 2 | 15 |
| 7 |
|
Melipilla | 11 | 4 | 3 | 4 | 11:11 | 0 | 15 |
| 8 |
|
Copiapó | 11 | 3 | 4 | 4 | 13:13 | 0 | 13 |
| 9 |
|
Santiago Wanderers | 12 | 3 | 4 | 5 | 11:14 | -3 | 13 |
| 10 |
|
Deportes Iquique | 11 | 2 | 5 | 4 | 8:11 | -3 | 11 |
| 11 |
|
Deportes Temuco | 11 | 2 | 5 | 4 | 11:16 | -5 | 11 |
| 12 |
|
Barnechea | 12 | 1 | 7 | 4 | 13:18 | -5 | 10 |
| 13 |
|
Fernández Vial | 11 | 1 | 7 | 3 | 8:13 | -5 | 10 |
| 14 |
|
San Luis | 11 | 2 | 4 | 5 | 11:17 | -6 | 10 |
| 15 |
|
Universidad de Concepción | 11 | 1 | 6 | 4 | 10:14 | -4 | 9 |
| 16 |
|
Recoleta | 11 | 1 | 5 | 5 | 8:13 | -5 | 8 |
| 17 |
|
Santa Cruz | 11 | 0 | 5 | 6 | 9:17 | -8 | 5 |
| Promotie | |
| Play-offs | |
| Degradatie |
