| 8. Ronde | 12.04.2022 | Santa Cruz | - | Universidad de Concepción | 0:0 | ||||
| 10. Ronde | 21.04.2022 | Rangers | - | Santa Cruz | 2:1 | ||||
| 11. Ronde | 26.04.2022 | Santa Cruz | - | Deportes Copiapó | 2:2 | ||||
| 12. Ronde | 30.04.2022 | Puerto Montt | - | Santa Cruz | 3:0 | ||||
| 13. Ronde | 08.05.2022 | Santa Cruz | - | Recoleta | 1:0 | ||||
| 14. Ronde | 13.05.2022 | Unión San Felipe | - | Santa Cruz | 2:1 | ||||
| 16. Ronde | 22.05.2022 | Deportes Melipilla | - | Santa Cruz | 1:0 | ||||
| 17. Ronde | 28.05.2022 | Santa Cruz | - | Santiago Wanderers | 2:0 |
Chili