| 22. Ronde | 05.02.2022 | Zamora CF | - | SD Logroñés | 0:0 | ||||
| 23. Ronde | 12.02.2022 | Athletic Club B | - | Zamora CF | 1:0 | ||||
| 24. Ronde | 20.02.2022 | Zamora CF | - | UD SS Reyes | 0:3 | ||||
| 25. Ronde | 26.02.2022 | CD Badajoz | - | Zamora CF | 0:0 | ||||
| 26. Ronde | 06.03.2022 | Zamora CF | - | Inter de Madrid | 0:2 | ||||
| 27. Ronde | 13.03.2022 | Racing Santander | - | Zamora CF | 2:1 | ||||
| 28. Ronde | 20.03.2022 | Zamora CF | - | Celta de Vigo B | 1:0 | ||||
| 31. Ronde | 10.04.2022 | Zamora CF | - | Real Unión | 0:1 | ||||
| 32. Ronde | 15.04.2022 | Racing Ferrol | - | Zamora CF | 1:3 |  |
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| 33. Ronde | 23.04.2022 | Zamora CF | - | CD Tudelano | 0:0 | ||||
| 34. Ronde | 01.05.2022 | Cultural Leonesa | - | Zamora CF | 0:0 | ||||
| 35. Ronde | 08.05.2022 | UD Logroñés | - | Zamora CF | 4:1 | ||||
| 37. Ronde | 21.05.2022 | Rayo Majadahonda | - | Zamora CF | 3:2 | ||||
| 38. Ronde | 28.05.2022 | Zamora CF | - | Real Valladolid B | 2:0 |
Panama