| 1. Ronde | 12.09.2021 | AEK Athene | - | Ionikos Nikea | 3:0 | ||||
| 2. Ronde | 19.09.2021 | OFI Heraklion | - | AEK Athene | 3:3 | ||||
| 3. Ronde | 22.09.2021 | AEK Athene | - | Lamia | 1:0 | ||||
| 4. Ronde | 26.09.2021 | PAOK Saloniki | - | AEK Athene | 2:0 | ||||
| 5. Ronde | 03.10.2021 | Panetolikos | - | AEK Athene | 1:3 | ||||
| 8. Ronde | 31.10.2021 | AEK Athene | - | Aris Saloniki | 2:1 | ||||
| 9. Ronde | 06.11.2021 | Apollon Smyrnis | - | AEK Athene | 2:2 | ||||
| 10. Ronde | 21.11.2021 | AEK Athene | - | Olympiakos | 2:3 | ||||
| 11. Ronde | 27.11.2021 | PAS Giannina | - | AEK Athene | 1:2 | ||||
| 12. Ronde | 05.12.2021 | AEK Athene | - | Panathinaikos | 1:0 | ||||
| 13. Ronde | 11.12.2021 | Asteras Tripolis | - | AEK Athene | 0:0 | ||||
| 14. Ronde | 16.12.2021 | Ionikos Nikea | - | AEK Athene | 0:1 | ||||
| 15. Ronde | 20.12.2021 | AEK Athene | - | OFI Heraklion | 1:2 | ||||
| 19. Ronde | 23.01.2022 | Atromitos | - | AEK Athene | 0:2 | ||||
| 20. Ronde | 30.01.2022 | AEK Athene | - | Volos NFC | 1:2 | ||||
| 22. Ronde | 06.02.2022 | AEK Athene | - | Apollon Smyrnis | 3:0 | ||||
| 24. Ronde | 20.02.2022 | AEK Athene | - | PAS Giannina | 2:0 | ||||
| 17. Ronde | 02.03.2022 | AEK Athene | - | PAOK Saloniki | 1:1 | ||||
| 26. Ronde | 06.03.2022 | AEK Athene | - | Asteras Tripolis | 2:1 |  |
Frankrijk