| 1. Ronde | 28.08.2022 | APOEL Nicosia | - | Paphos FC | 1:1 | ||||
| 2. Ronde | 04.09.2022 | Anorthosis Famagusta | - | APOEL Nicosia | 0:2 |  |
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| 3. Ronde | 10.09.2022 | APOEL Nicosia | - | Aris Limassol | 0:1 | ||||
| 4. Ronde | 17.09.2022 | Olympiakos Nikosia | - | APOEL Nicosia | 0:2 | ||||
| 5. Ronde | 02.10.2022 | APOEL Nicosia | - | AEL Limassol | 0:0 | ||||
| 7. Ronde | 16.10.2022 | Akritas Chlorakas | - | APOEL Nicosia | 1:2 |  |
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| 8. Ronde | 22.10.2022 | APOEL Nicosia | - | AEK Larnaca | 1:0 | ||||
| 10. Ronde | 04.11.2022 | APOEL Nicosia | - | Enosis Neon Paralimni | 2:0 | ||||
| 11. Ronde | 13.11.2022 | Doxa Katokopias | - | APOEL Nicosia | 0:1 | ||||
| 12. Ronde | 27.11.2022 | APOEL Nicosia | - | Omonia Nikosia | 4:0 | ||||
| 13. Ronde | 03.12.2022 | Nea Salamina | - | APOEL Nicosia | 1:3 | |
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| 14. Ronde | 09.12.2022 | Paphos FC | - | APOEL Nicosia | 1:2 | ||||
| 15. Ronde | 17.12.2022 | APOEL Nicosia | - | Anorthosis Famagusta | 1:0 | ||||
| 16. Ronde | 22.12.2022 | Aris Limassol | - | APOEL Nicosia | 1:1 |
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