| 2. Ronde | 12.09.2021 | CD Marchamalo | - | UD Melilla | 0:0 | ||||
| 3. Ronde | 19.09.2021 | Águilas FC | - | CD Marchamalo | 2:0 | ||||
| 4. Ronde | 26.09.2021 | CD Marchamalo | - | Atlético Mancha Real | 0:0 |  |
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| 5. Ronde | 03.10.2021 | CD Toledo | - | CD Marchamalo | 3:2 | |
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| 6. Ronde | 10.10.2021 | CD Marchamalo | - | CS Puertollano CF | 0:0 |
Spanje