| 3. Ronde | 22.01.2022 | Club Tijuana [U16] | - | Atlético San Luis [U16] | 2:0 | ||||
| 4. Ronde | 29.01.2022 | UANL Tigres [U16] | - | Club Tijuana [U16] | 3:0 | ||||
| 6. Ronde | 12.02.2022 | Mazatlán FC [U16] | - | Club Tijuana [U16] | 1:2 | ||||
| 14. Ronde | 05.04.2022 | Atlético San Luis [U16] | - | Club Tijuana [U16] | 3:1 |  |
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| 15. Ronde | 20.04.2022 | Club Tijuana [U16] | - | Santos Laguna [U16] | 0:1 |
Mexico