| 1. Ronde | 21.08.2021 | Paphos FC | - | APOEL Nicosia | 4:0 | ||||
| 2. Ronde | 13.09.2021 | AEL Limassol | - | Paphos FC | 4:0 | ||||
| 4. Ronde | 26.09.2021 | Omonia Nikosia | - | Paphos FC | 1:1 | ||||
| 8. Ronde | 01.11.2021 | Paphos FC | - | PAEEK | 2:0 | ||||
| 9. Ronde | 07.11.2021 | Anorthosis Famagusta | - | Paphos FC | 1:0 | ||||
| 10. Ronde | 20.11.2021 | Paphos FC | - | Ethnikos Achna | 3:0 | ||||
| 13. Ronde | 10.12.2021 | Paphos FC | - | AEL Limassol | 1:0 | ||||
| 17. Ronde | 15.01.2022 | Olympiakos Nikosia | - | Paphos FC | 1:2 | ||||
| 18. Ronde | 22.01.2022 | Paphos FC | - | Apollon Limassol | 0:1 | ||||
| 19. Ronde | 28.01.2022 | PAEEK | - | Paphos FC | 0:2 | ||||
| 20. Ronde | 06.02.2022 | Paphos FC | - | Anorthosis Famagusta | 1:1 | ||||
| 21. Ronde | 13.02.2022 | Ethnikos Achna | - | Paphos FC | 0:1 | ||||
| 16. Ronde | 18.02.2022 | Doxa Katokopias | - | Paphos FC | 1:1 | ||||
| 22. Ronde | 25.02.2022 | Paphos FC | - | Aris Limassol | 1:1 |
Portugal