| 1. Ronde | 18.08.2021 | F91 Dudelange | - | FC Wiltz 71 | 3:0 | ||||
| 3. Ronde | 22.08.2021 | Jeunesse Esch | - | F91 Dudelange | 0:3 | ||||
| 4. Ronde | 28.08.2021 | F91 Dudelange | - | US Hostert | 2:2 | ||||
| 5. Ronde | 12.09.2021 | RFCU Luxemburg | - | F91 Dudelange | 3:4 | ||||
| 6. Ronde | 18.09.2021 | F91 Dudelange | - | Union Titus Pétange | 3:1 | ||||
| 7. Ronde | 22.09.2021 | US Mondorf | - | F91 Dudelange | 0:1 | ||||
| 8. Ronde | 26.09.2021 | F91 Dudelange | - | Etzella Ettelbruck | 6:1 | ||||
| 9. Ronde | 17.10.2021 | FC Differdange 03 | - | F91 Dudelange | 3:2 | ||||
| 10. Ronde | 24.10.2021 | F91 Dudelange | - | Victoria Rosport | 4:1 | ||||
| 11. Ronde | 06.11.2021 | CS FOLA Esch | - | F91 Dudelange | 0:3 | ||||
| 12. Ronde | 21.11.2021 | F91 Dudelange | - | UNA Strassen | 1:1 | ||||
| 13. Ronde | 28.11.2021 | Swift Hesperange | - | F91 Dudelange | 1:0 | ||||
| 14. Ronde | 04.12.2021 | F91 Dudelange | - | FC Rodange 91 | 5:1 | ||||
| 15. Ronde | 11.12.2021 | RM Hamm Benfica | - | F91 Dudelange | 0:4 | ||||
| 25. Ronde | 16.04.2022 | F91 Dudelange | - | CS FOLA Esch | 2:3 |
Luxemburg