| 1. Ronde | 05.09.2021 | UD Tamaraceite | - | UD San Fernando | 3:4 |  |
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| 2. Ronde | 12.09.2021 | UD San Fernando | - | UD Montijo | 1:2 | |
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| 3. Ronde | 19.09.2021 | UD San Fernando | - | CD Mensajero | 0:1 | ||||
| 7. Ronde | 17.10.2021 | UD San Fernando | - | CP Cacereño | 1:1 | |
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| 8. Ronde | 24.10.2021 | CF Villanovense | - | UD San Fernando | 2:0 | |
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| 9. Ronde | 31.10.2021 | UD San Fernando | - | Mérida AD | 0:1 | ||||
| 10. Ronde | 07.11.2021 | UD Las Palmas B | - | UD San Fernando | 1:0 | ||||
| 11. Ronde | 14.11.2021 | UD San Fernando | - | CF Panadería Pulido | 1:0 | |
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| 13. Ronde | 28.11.2021 | UD San Fernando | - | Vélez CF | 0:0 | |
Spanje