| 5. Ronde | 05.02.2022 | Deportivo Toluca [U16] | - | Cruz Azul [U16] | 0:4 | ||||
| 9. Ronde | 05.03.2022 | Cruz Azul [U16] | - | CF América [U16] | 3:2 | ||||
| 10. Ronde | 12.03.2022 | CF Pachuca [U16] | - | Cruz Azul [U16] | 2:2 | ||||
| 11. Ronde | 19.03.2022 | Gallos Blancos [U16] | - | Cruz Azul [U16] | 1:1 | ||||
| 12. Ronde | 26.03.2022 | Cruz Azul [U16] | - | FC Juárez [U16] | 7:3 |  |
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| 13. Ronde | 02.04.2022 | Cruz Azul [U16] | - | Deportivo Toluca [U16] | 0:1 | ||||
| 16. Ronde | 23.04.2022 | Puebla FC [U16] | - | Cruz Azul [U16] | 2:3 |
Mexico