| 1. Ronde | 18.07.2021 | Luki-Energiya Velikiye Luki | - | Zenit St. Petersburg 2 | 3:3 | ||||
| 3. Ronde | 01.08.2021 | Zenit St. Petersburg 2 | - | Zvezda St. Petersburg | 2:1 | ||||
| 4. Ronde | 07.08.2021 | Dinamo St. Petersburg | - | Zenit St. Petersburg 2 | 2:0 | ||||
| 8. Ronde | 04.09.2021 | FK Tver | - | Zenit St. Petersburg 2 | 2:2 | ||||
| 9. Ronde | 10.09.2021 | Zenit St. Petersburg 2 | - | FK Leningradets | 1:1 |  |
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| 11. Ronde | 18.09.2021 | Zenit St. Petersburg 2 | - | Baltika Kaliningrad 2 | 2:1 | ||||
| 13. Ronde | 30.09.2021 | Zvezda St. Petersburg | - | Zenit St. Petersburg 2 | 3:0 | ||||
| 14. Ronde | 04.10.2021 | Zenit St. Petersburg 2 | - | Dinamo St. Petersburg | 1:2 | ||||
| 15. Ronde | 10.10.2021 | FK Kairat Moskva | - | Zenit St. Petersburg 2 | 3:0 | ||||
| 16. Ronde | 14.10.2021 | Zenit St. Petersburg 2 | - | FK Krasava | 1:0 | ||||
| 17. Ronde | 19.10.2021 | FK Chita | - | Zenit St. Petersburg 2 | 1:0 | ||||
| 19. Ronde | 31.10.2021 | FK Leningradets | - | Zenit St. Petersburg 2 | 7:1 | |
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| 21. Ronde | 10.11.2021 | Baltika Kaliningrad 2 | - | Zenit St. Petersburg 2 | 2:1 |
Rusland