| 7. Ronde | 17.10.2021 | CD Marchamalo | - | Recreativo Granada | 0:1 |  |
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| 8. Ronde | 24.10.2021 | CF Intercity | - | CD Marchamalo | 3:0 | ||||
| 9. Ronde | 31.10.2021 | CD Marchamalo | - | Mar Menor CF | 2:0 |  |
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| 10. Ronde | 06.11.2021 | UD Alzira | - | CD Marchamalo | 1:0 | ||||
| 11. Ronde | 14.11.2021 | CD Marchamalo | - | UD Socuéllamos | 1:2 | ||||
| 12. Ronde | 21.11.2021 | CA Pulpileño | - | CD Marchamalo | 1:1 | ||||
| 13. Ronde | 27.11.2021 | CD Marchamalo | - | Levante UD B | 1:7 | ||||
| 14. Ronde | 05.12.2021 | CD El Ejido 2012 | - | CD Marchamalo | 2:2 | |
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| 15. Ronde | 12.12.2021 | CD Marchamalo | - | CF La Nucía | 0:3 |
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