| 1. Ronde | 04.09.2021 | UD Logroñés Promesas | - | UD Mutilvera | 2:3 |  |
|||
| 2. Ronde | 11.09.2021 | UD Mutilvera | - | Náxara CD | 3:2 | |
|||
| 3. Ronde | 18.09.2021 | UD Mutilvera | - | CD Izarra | 1:1 | ||||
| 5. Ronde | 02.10.2021 | UD Mutilvera | - | CD Laredo | 1:0 | |
|||
| 6. Ronde | 09.10.2021 | Real Sociedad C | - | UD Mutilvera | 3:1 | |
 |
||
| 7. Ronde | 16.10.2021 | UD Mutilvera | - | AD San Juan | 2:1 | |
|||
| 8. Ronde | 24.10.2021 | Arenas de Getxo | - | UD Mutilvera | 1:3 | |
|||
| 9. Ronde | 30.10.2021 | UD Mutilvera | - | Burgos Promesas | 1:2 | ||||
| 10. Ronde | 07.11.2021 | Racing Rioja CF | - | UD Mutilvera | 1:0 | ||||
| 11. Ronde | 13.11.2021 | UD Mutilvera | - | CF Ardoi | 1:2 | ||||
| 12. Ronde | 21.11.2021 | Peña Sport FC | - | UD Mutilvera | 2:1 | |
|||
| 13. Ronde | 27.11.2021 | UD Mutilvera | - | CD Cayón | 2:1 | |
|||
| 14. Ronde | 05.12.2021 | Rayo Cantabria | - | UD Mutilvera | 0:0 | ||||
| 15. Ronde | 11.12.2021 | UD Mutilvera | - | Sestao River | 1:1 | ||||
| 16. Ronde | 18.12.2021 | CA Osasuna B | - | UD Mutilvera | 2:0 |
Spanje