| 2. Ronde | 03.09.2021 | CF Talavera | - | UD SS Reyes | 2:0 | ||||
| 3. Ronde | 12.09.2021 | UD SS Reyes | - | Rayo Majadahonda | 2:1 |  |
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| 6. Ronde | 02.10.2021 | UD Logroñés | - | UD SS Reyes | 1:0 | ||||
| 7. Ronde | 10.10.2021 | UD SS Reyes | - | Inter de Madrid | 1:0 | ||||
| 8. Ronde | 16.10.2021 | Deportivo La Coruña | - | UD SS Reyes | 1:0 | ||||
| 9. Ronde | 24.10.2021 | UD SS Reyes | - | CD Badajoz | 0:0 | ||||
| 11. Ronde | 07.11.2021 | UD SS Reyes | - | Real Unión | 0:2 | |
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| 12. Ronde | 14.11.2021 | UD SS Reyes | - | Zamora CF | 3:1 | ||||
| 20. Ronde | 26.01.2022 | CD Badajoz | - | UD SS Reyes | 2:1 | ||||
| 23. Ronde | 13.02.2022 | UD SS Reyes | - | CF Talavera | 1:0 | ||||
| 24. Ronde | 20.02.2022 | Zamora CF | - | UD SS Reyes | 0:3 | ||||
| 25. Ronde | 27.02.2022 | UD SS Reyes | - | Deportivo La Coruña | 0:0 | |
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| 26. Ronde | 05.03.2022 | SD Logroñés | - | UD SS Reyes | 1:0 | ||||
| 27. Ronde | 12.03.2022 | UD SS Reyes | - | CD Calahorra | 0:3 | ||||
| 28. Ronde | 19.03.2022 | Real Unión | - | UD SS Reyes | 0:1 | ||||
| 29. Ronde | 27.03.2022 | Racing Ferrol | - | UD SS Reyes | 1:0 | |
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| 32. Ronde | 17.04.2022 | UD SS Reyes | - | Cultural Leonesa | 0:3 | ||||
| 33. Ronde | 24.04.2022 | Inter de Madrid | - | UD SS Reyes | 0:0 | |
Spanje