| 1. Ronde | 28.08.2021 | Albacete | - | CD Castellón | 3:1 | ||||
| 2. Ronde | 05.09.2021 | Atlético Baleares | - | Albacete | 4:1 | ||||
| 3. Ronde | 11.09.2021 | Albacete | - | FC Andorra | 1:0 | ||||
| 5. Ronde | 26.09.2021 | Albacete | - | Real Madrid Castilla | 2:0 | ||||
| 6. Ronde | 03.10.2021 | UE Costa Brava | - | Albacete | 0:3 | ||||
| 7. Ronde | 09.10.2021 | Albacete | - | Real Betis B | 1:1 | ||||
| 8. Ronde | 17.10.2021 | Sevilla Atlético | - | Albacete | 0:1 | ||||
| 9. Ronde | 24.10.2021 | UE Cornellà | - | Albacete | 1:0 | ||||
| 10. Ronde | 30.10.2021 | Albacete | - | San Fernando CD | 1:0 |  |
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| 11. Ronde | 06.11.2021 | Albacete | - | Linares Deportivo | 1:0 | ||||
| 12. Ronde | 13.11.2021 | RB Linense | - | Albacete | 4:1 | ||||
| 31. Ronde | 10.04.2022 | Albacete | - | Atlético Sanluqueño CF | 4:0 | ||||
| 37. Ronde | 21.05.2022 | Real Betis B | - | Albacete | 0:2 |
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