| 5. Ronde | 03.10.2021 | CD Eldense | - | CA Pulpileño | 0:3 | ||||
| 7. Ronde | 17.10.2021 | CD Eldense | - | CD El Ejido 2012 | 3:1 | ||||
| 8. Ronde | 24.10.2021 | CF La Nucía | - | CD Eldense | 1:0 | ||||
| 9. Ronde | 31.10.2021 | CS Puertollano CF | - | CD Eldense | 0:1 | ||||
| 10. Ronde | 07.11.2021 | CD Eldense | - | Hércules CF | 2:2 | ||||
| 11. Ronde | 14.11.2021 | Real Murcia | - | CD Eldense | 1:2 | ||||
| 12. Ronde | 21.11.2021 | CD Eldense | - | UD Melilla | 2:1 | ||||
| 13. Ronde | 27.11.2021 | Águilas FC | - | CD Eldense | 0:1 | ||||
| 14. Ronde | 05.12.2021 | CD Eldense | - | Atlético Mancha Real | 0:1 |  |
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| 15. Ronde | 12.12.2021 | CD Toledo | - | CD Eldense | 1:1 | ||||
| 16. Ronde | 18.12.2021 | CD Eldense | - | CD Marchamalo | 4:0 | ||||
| 17. Ronde | 09.01.2022 | Recreativo Granada | - | CD Eldense | 1:1 | ||||
| 19. Ronde | 30.01.2022 | CD Eldense | - | Mar Menor CF | 1:0 | ||||
| 23. Ronde | 27.02.2022 | CD Eldense | - | Levante UD B | 1:3 | ||||
| 26. Ronde | 20.03.2022 | CD Eldense | - | CS Puertollano CF | 3:2 |
Spanje