| 1. Ronde | 29.08.2021 | CD Badajoz | - | CF Talavera | 2:0 | ||||
| 2. Ronde | 03.09.2021 | CF Talavera | - | UD SS Reyes | 2:0 | ||||
| 3. Ronde | 11.09.2021 | Racing Santander | - | CF Talavera | 5:1 | ||||
| 4. Ronde | 19.09.2021 | CF Talavera | - | CD Calahorra | 0:0 | ||||
| 5. Ronde | 26.09.2021 | SD Logroñés | - | CF Talavera | 3:2 | ||||
| 7. Ronde | 09.10.2021 | Cultural Leonesa | - | CF Talavera | 1:2 | ||||
| 11. Ronde | 06.11.2021 | CD Tudelano | - | CF Talavera | 0:2 | ||||
| 12. Ronde | 14.11.2021 | CF Talavera | - | Racing Ferrol | 1:2 | ||||
| 13. Ronde | 21.11.2021 | Athletic Club B | - | CF Talavera | 0:1 | ||||
| 16. Ronde | 12.12.2021 | Celta de Vigo B | - | CF Talavera | 2:0 | ||||
| 17. Ronde | 19.12.2021 | CF Talavera | - | Real Unión | 1:3 | ||||
| 19. Ronde | 23.01.2022 | CF Talavera | - | Zamora CF | 0:1 | ||||
| 20. Ronde | 27.01.2022 | Extremadura UD | - | CF Talavera | 0:2 | ||||
| 21. Ronde | 30.01.2022 | CF Talavera | - | CD Tudelano | 2:1 |
Spanje