| 9. Ronde | 31.10.2021 | Águilas FC | - | CA Pulpileño | 0:0 | ||||
| 10. Ronde | 07.11.2021 | Levante UD B | - | Águilas FC | 2:0 | ||||
| 11. Ronde | 14.11.2021 | Águilas FC | - | CD El Ejido 2012 | 0:1 | ||||
| 12. Ronde | 21.11.2021 | CF La Nucía | - | Águilas FC | 0:0 | ||||
| 13. Ronde | 27.11.2021 | Águilas FC | - | CD Eldense | 0:1 | ||||
| 14. Ronde | 05.12.2021 | Hércules CF | - | Águilas FC | 2:1 | ||||
| 15. Ronde | 12.12.2021 | Águilas FC | - | Real Murcia | 1:2 | ||||
| 28. Ronde | 03.04.2022 | CD El Ejido 2012 | - | Águilas FC | 1:0 |  |
Portugal