| 5. Ronde | 26.09.2021 | SD Logroñés | - | CF Talavera | 3:2 |  |
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| 8. Ronde | 16.10.2021 | SD Logroñés | - | Zamora CF | 2:0 | ||||
| 11. Ronde | 06.11.2021 | Racing Ferrol | - | SD Logroñés | 0:2 | ||||
| 13. Ronde | 21.11.2021 | SD Logroñés | - | Real Unión | 0:2 | ||||
| 18. Ronde | 09.01.2022 | Celta de Vigo B | - | SD Logroñés | 3:2 | ||||
| 22. Ronde | 05.02.2022 | Zamora CF | - | SD Logroñés | 0:0 | ||||
| 23. Ronde | 13.02.2022 | SD Logroñés | - | Deportivo La Coruña | 1:0 | ||||
| 26. Ronde | 05.03.2022 | SD Logroñés | - | UD SS Reyes | 1:0 | |
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| 27. Ronde | 13.03.2022 | Cultural Leonesa | - | SD Logroñés | 2:2 | |
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| 28. Ronde | 19.03.2022 | SD Logroñés | - | Racing Ferrol | 0:2 | ||||
| 37. Ronde | 21.05.2022 | Inter de Madrid | - | SD Logroñés | 3:1 |  |
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| 38. Ronde | 28.05.2022 | SD Logroñés | - | Celta de Vigo B | 1:1 | |
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