| 2. Ronde | 24.09.2000 | Iraklis Saloniki | - | Panachaiki GE | 2:0 | ||||
| 3. Ronde | 01.10.2000 | Panachaiki GE | - | Athinaikos | 3:1 | ||||
| 4. Ronde | 30.10.2000 | Ethnikos Asteras | - | Panachaiki GE | 3:1 |  |
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| 6. Ronde | 12.11.2000 | AEK Athene | - | Panachaiki GE | 2:1 | ||||
| 7. Ronde | 19.11.2000 | Olympiakos | - | Panachaiki GE | 3:0 | |
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| 8. Ronde | 26.11.2000 | Panachaiki GE | - | PS Kalamata | 3:2 | ||||
| 9. Ronde | 03.12.2000 | PAS Giannina | - | Panachaiki GE | 1:1 |  |
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| 12. Ronde | 03.01.2001 | Panachaiki GE | - | OFI Heraklion | 2:1 | ||||
| 13. Ronde | 07.01.2001 | Paniliakos Pyrgos | - | Panachaiki GE | 2:2 | |
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| 14. Ronde | 14.01.2001 | Panachaiki GE | - | Panathinaikos | 1:2 | |
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| 15. Ronde | 21.01.2001 | Panachaiki GE | - | PAOK Saloniki | 1:2 | ||||
| 17. Ronde | 04.02.2001 | Panachaiki GE | - | Iraklis Saloniki | 1:2 | ||||
| 19. Ronde | 18.02.2001 | Panachaiki GE | - | Ethnikos Asteras | 1:0 | |
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| 22. Ronde | 11.03.2001 | Panachaiki GE | - | Olympiakos | 1:5 | ||||
| 23. Ronde | 18.03.2001 | PS Kalamata | - | Panachaiki GE | 3:3 | ||||
| 25. Ronde | 08.04.2001 | Panionios GSS | - | Panachaiki GE | 2:0 | |
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| 28. Ronde | 06.05.2001 | Panachaiki GE | - | Paniliakos Pyrgos | 3:0 |  |
Brazilië