| 1. Ronde | 05.09.2021 | CD Eldense | - | CF Intercity | 0:0 |  |
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| 2. Ronde | 12.09.2021 | Mar Menor CF | - | CD Eldense | 1:1 | |
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| 3. Ronde | 19.09.2021 | CD Eldense | - | UD Alzira | 1:1 | ||||
| 4. Ronde | 26.09.2021 | UD Socuéllamos | - | CD Eldense | 1:1 | ||||
| 5. Ronde | 03.10.2021 | CD Eldense | - | CA Pulpileño | 0:3 | |
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| 6. Ronde | 09.10.2021 | Levante UD B | - | CD Eldense | 1:1 | ||||
| 7. Ronde | 17.10.2021 | CD Eldense | - | CD El Ejido 2012 | 3:1 | |
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| 8. Ronde | 24.10.2021 | CF La Nucía | - | CD Eldense | 1:0 | ||||
| 9. Ronde | 31.10.2021 | CS Puertollano CF | - | CD Eldense | 0:1 |  |
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| 10. Ronde | 07.11.2021 | CD Eldense | - | Hércules CF | 2:2 | |
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| 12. Ronde | 21.11.2021 | CD Eldense | - | UD Melilla | 2:1 | ||||
| 13. Ronde | 27.11.2021 | Águilas FC | - | CD Eldense | 0:1 | ||||
| 14. Ronde | 05.12.2021 | CD Eldense | - | Atlético Mancha Real | 0:1 | |
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| 15. Ronde | 12.12.2021 | CD Toledo | - | CD Eldense | 1:1 |  |
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| 17. Ronde | 09.01.2022 | Recreativo Granada | - | CD Eldense | 1:1 |
Spanje