| 3. Ronde | 01.11.2020 | Real Murcia | - | Sevilla Atlético | 1:1 |  |
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| 4. Ronde | 08.11.2020 | Lorca Deportiva | - | Real Murcia | 1:2 | ||||
| 1. Ronde | 15.11.2020 | Real Murcia | - | Recreativo Granada | 1:2 | ||||
| 5. Ronde | 21.11.2020 | Real Murcia | - | Linares Deportivo | 3:0 | ||||
| 2. Ronde | 25.11.2020 | Real Betis B | - | Real Murcia | 2:1 | |
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| 6. Ronde | 29.11.2020 | Yeclano Deportivo | - | Real Murcia | 1:2 | |
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| 7. Ronde | 06.12.2020 | Real Murcia | - | Córdoba CF | 0:1 | ||||
| 8. Ronde | 13.12.2020 | Real Murcia | - | UCAM Murcia CF | 2:1 |  |
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| 10. Ronde | 17.01.2021 | Recreativo Granada | - | Real Murcia | 0:1 | ||||
| 11. Ronde | 23.01.2021 | Real Murcia | - | Real Betis B | 0:2 | |
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| 12. Ronde | 31.01.2021 | Sevilla Atlético | - | Real Murcia | 1:1 | ||||
| 13. Ronde | 07.02.2021 | Real Murcia | - | Lorca Deportiva | 1:1 | ||||
| 14. Ronde | 14.02.2021 | Linares Deportivo | - | Real Murcia | 2:0 | ||||
| 15. Ronde | 21.02.2021 | Real Murcia | - | Yeclano Deportivo | 1:0 | ||||
| 16. Ronde | 07.03.2021 | Córdoba CF | - | Real Murcia | 2:2 | |
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