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| 06.11.2021 | 13:00 | Leotar Trebinje | - | Široki Brijeg | 1:3 (1:1) | |
| 17:00 | Radnik Bijeljina | - | FK Sarajevo | 0:1 (0:1) | ||
| 19:00 | Zrinjski Mostar | - | Borac Banja Luka | 4:1 (4:0) | ||
| 07.11.2021 | 13:00 | HŠK Posušje | - | FK Tuzla City | 1:1 (0:0) | |
| 13:00 | FK Rudar | - | Željezničar Sarajevo | 2:2 (1:1) | ||
| 08.11.2021 | 18:00 | Sloboda Tuzla | - | Velež Mostar | 1:1 (0:1) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Zrinjski Mostar | 16 | 12 | 3 | 1 | 31:5 | 26 | 39 |
| 2 |
|
FK Tuzla City | 16 | 9 | 5 | 2 | 30:16 | 14 | 32 |
| 3 |
|
FK Sarajevo | 16 | 7 | 4 | 5 | 16:12 | 4 | 25 |
| 4 |
|
Sloboda Tuzla | 16 | 5 | 8 | 3 | 16:11 | 5 | 23 |
| 5 |
|
Borac Banja Luka | 16 | 5 | 8 | 3 | 22:21 | 1 | 23 |
| 6 |
|
Široki Brijeg | 16 | 5 | 8 | 3 | 15:14 | 1 | 23 |
| 7 |
|
Željezničar Sarajevo | 16 | 4 | 7 | 5 | 12:18 | -6 | 19 |
| 8 |
|
Leotar Trebinje | 16 | 4 | 4 | 8 | 11:21 | -10 | 16 |
| 9 |
|
FK Rudar | 16 | 3 | 6 | 7 | 19:23 | -4 | 15 |
| 10 |
|
Velež Mostar | 16 | 4 | 5 | 7 | 17:22 | -5 | 14 |
| 11 |
|
HŠK Posušje | 16 | 2 | 6 | 8 | 13:27 | -14 | 12 |
| 12 |
|
Radnik Bijeljina | 16 | 2 | 4 | 10 | 12:24 | -12 | 10 |
| Champions League Kwali. | |
| Degradatie |
