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| U | Avaí - SC | - | Brusque - SC | 0:0 (0:0) | ||
| R | Brusque - SC | - | Avaí - SC | 0:1 (0:0) | ||
| U: 02.05.2021 21:00 | R: 20.05.2021 01:30 | Winnaars: Avaí - SC | ||||
| U | Marcílio Dias - SC | - | Chapecoense | 1:4 (1:1) | ||
| R | Chapecoense | - | Marcílio Dias - SC | 1:1 (0:1) | ||
| U: 16.05.2021 21:00 | R: 19.05.2021 20:30 | Winnaars: Chapecoense | ||||
