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| U | Palmeiras | - | IAPE - MA | 3:0 (2:0) | ||
| R | IAPE - MA | - | Palmeiras | 0:2 (0:1) | ||
| U: 15.10.2022 16:00 | R: 22.10.2022 20:00 | Winnaars: Palmeiras | ||||
| U | Remo - PA | - | Internacional | 0:3 (0:1) | ||
| R | Internacional | - | Remo - PA | 4:0 (3:0) | ||
| U: 16.10.2022 21:00 | R: 22.10.2022 20:00 | Winnaars: Internacional | ||||
| U | Flamengo RJ | - | Fluminense - PI | 3:1 (1:0) | ||
| R | Fluminense - PI | - | Flamengo RJ | 0:1 (0:1) | ||
| U: 17.10.2022 20:00 | R: 23.10.2022 20:00 | Winnaars: Flamengo RJ | ||||
| U | Cruzeiro | - | Ceará - CE | 1:2 (0:1) | ||
| R | Ceará - CE | - | Cruzeiro | 4:1 (2:0) | ||
| U: 19.10.2022 22:00 | R: 24.10.2022 20:30 | Winnaars: Ceará - CE | ||||
