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| 16.04.2022 | 18:00 | Blois Foot 41 | - | Vannes OC | 5:2 (2:1) | |
| 18:00 | SM Caen (CFA) | - | AS Poissy | 0:3 (0:0) | ||
| 18:00 | EA Guingamp (CFA) | - | C'Chartres Football | 3:4 (1:2) | ||
| 18:00 | St-Pryvé St-Hilaire | - | US Granvillaise | 0:3 (0:2) | ||
| 18:00 | Stade Plabennec | - | SO Romorantin | 2:1 (1:0) | ||
| 18:00 | US Saint-Malo | - | FC Rouen 1899 | 1:4 (1:3) | ||
| 18:00 | FC Versailles | - | AS Vitré | 3:0 (3:0) | ||
| 19:00 | FC Lorient (CFA) | - | Châteaubriant Voltigeurs | 0:0 (0:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Versailles | 25 | 14 | 10 | 1 | 38:13 | 25 | 52 |
| 2 |
|
FC Lorient (CFA) | 25 | 14 | 6 | 5 | 39:19 | 20 | 48 |
| 3 |
|
C'Chartres Football | 25 | 14 | 3 | 8 | 47:37 | 10 | 45 |
| 4 |
|
Blois Foot 41 | 25 | 11 | 6 | 8 | 42:42 | 0 | 39 |
| 5 |
|
Vannes OC | 25 | 10 | 7 | 8 | 39:35 | 4 | 37 |
| 6 |
|
St-Pryvé St-Hilaire | 25 | 10 | 6 | 9 | 32:31 | 1 | 36 |
| 7 |
|
FC Rouen 1899 | 25 | 8 | 10 | 7 | 29:25 | 4 | 34 |
| 8 |
|
Châteaubriant Voltigeurs | 25 | 9 | 6 | 10 | 26:28 | -2 | 33 |
| 9 |
|
AS Poissy | 25 | 7 | 11 | 7 | 30:31 | -1 | 32 |
| 10 |
|
SM Caen (CFA) | 25 | 8 | 6 | 11 | 24:35 | -11 | 30 |
| 11 |
|
EA Guingamp (CFA) | 25 | 7 | 8 | 10 | 32:41 | -9 | 29 |
| 12 |
|
US Granvillaise | 25 | 5 | 13 | 7 | 25:25 | 0 | 28 |
| 13 |
|
US Saint-Malo | 25 | 7 | 5 | 13 | 22:34 | -12 | 26 |
| 14 |
|
Stade Plabennec | 25 | 6 | 7 | 12 | 25:31 | -6 | 25 |
| 15 |
|
SO Romorantin | 25 | 6 | 6 | 13 | 22:36 | -14 | 24 |
| 16 |
|
AS Vitré | 25 | 5 | 8 | 12 | 27:36 | -9 | 23 |
| Promotie | |
| Degradatie |
