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| 16.04.2022 | 17:00 | GOAL FC | - | AS Monaco (CFA) | 5:0 (4:0) | |
| 18:00 | Aubagne FC | - | Lyon-La Duchère | 1:1 (1:1) | ||
| 18:00 | Étoile FC | - | FC Martigues | 1:3 (1:1) | ||
| 18:00 | Olympique Marseille (CFA) | - | Louhans-Cuiseaux | 1:3 (1:2) | ||
| 18:00 | AS Saint-Priest | - | GFA Rumilly Vallières | 1:0 (1:0) | ||
| 18:00 | SC Toulon | - | Olympique Lyon (CFA) | 2:1 (0:1) | ||
| 18:00 | Marignane Gignac FC | - | RC Grasse | 1:2 (0:2) | ||
| 18:00 | Jura Sud | - | Hyères FC | 1:0 (0:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
GOAL FC | 25 | 14 | 8 | 3 | 46:17 | 29 | 50 |
| 2 |
|
FC Martigues | 25 | 13 | 8 | 4 | 36:24 | 12 | 47 |
| 3 |
|
RC Grasse | 25 | 12 | 8 | 5 | 31:23 | 8 | 44 |
| 4 |
|
Louhans-Cuiseaux | 25 | 10 | 9 | 6 | 36:23 | 13 | 39 |
| 5 |
|
Aubagne FC | 25 | 9 | 10 | 6 | 32:24 | 8 | 37 |
| 6 |
|
Étoile FC | 25 | 10 | 7 | 8 | 28:24 | 4 | 37 |
| 7 |
|
Marignane Gignac FC | 25 | 10 | 5 | 10 | 28:26 | 2 | 35 |
| 8 |
|
Jura Sud | 25 | 10 | 5 | 10 | 33:37 | -4 | 35 |
| 9 |
|
Olympique Lyon (CFA) | 25 | 9 | 7 | 9 | 26:32 | -6 | 34 |
| 10 |
|
Hyères FC | 25 | 7 | 10 | 8 | 27:29 | -2 | 31 |
| 11 |
|
SC Toulon | 25 | 7 | 9 | 9 | 25:25 | 0 | 30 |
| 12 |
|
AS Saint-Priest | 25 | 8 | 4 | 13 | 28:35 | -7 | 28 |
| 13 |
|
Lyon-La Duchère | 25 | 6 | 9 | 10 | 27:33 | -6 | 27 |
| 14 |
|
AS Monaco (CFA) | 25 | 6 | 7 | 12 | 24:37 | -13 | 25 |
| 15 |
|
GFA Rumilly Vallières | 25 | 6 | 7 | 12 | 19:31 | -12 | 25 |
| 16 |
|
Olympique Marseille (CFA) | 25 | 5 | 3 | 17 | 23:49 | -26 | 18 |
| Promotie | |
| Degradatie |
