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| 23.04.2022 | 16:00 | AS Monaco (CFA) | - | Aubagne FC | 1:1 (1:1) | |
| 18:00 | Hyères FC | - | Olympique Marseille (CFA) | 2:0 (1:0) | ||
| 18:00 | FC Martigues | - | GOAL FC | 3:2 (2:1) | ||
| 18:00 | GFA Rumilly Vallières | - | Étoile FC | 2:1 (1:1) | ||
| 18:00 | RC Grasse | - | Olympique Lyon (CFA) | 2:1 (1:1) | ||
| 18:00 | Louhans-Cuiseaux | - | Marignane Gignac FC | 0:0 (0:0) | ||
| 18:00 | Lyon-La Duchère | - | Jura Sud | 1:4 (0:2) | ||
| 18:00 | AS Saint-Priest | - | SC Toulon | 1:1 (0:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
GOAL FC | 26 | 14 | 8 | 4 | 48:20 | 28 | 50 |
| 2 |
|
FC Martigues | 26 | 14 | 8 | 4 | 39:26 | 13 | 50 |
| 3 |
|
RC Grasse | 26 | 13 | 8 | 5 | 33:24 | 9 | 47 |
| 4 |
|
Louhans-Cuiseaux | 26 | 10 | 10 | 6 | 36:23 | 13 | 40 |
| 5 |
|
Aubagne FC | 26 | 9 | 11 | 6 | 33:25 | 8 | 38 |
| 6 |
|
Jura Sud | 26 | 11 | 5 | 10 | 37:38 | -1 | 38 |
| 7 |
|
Étoile FC | 26 | 10 | 7 | 9 | 29:26 | 3 | 37 |
| 8 |
|
Marignane Gignac FC | 26 | 10 | 6 | 10 | 28:26 | 2 | 36 |
| 9 |
|
Hyères FC | 26 | 8 | 10 | 8 | 29:29 | 0 | 34 |
| 10 |
|
Olympique Lyon (CFA) | 26 | 9 | 7 | 10 | 27:34 | -7 | 34 |
| 11 |
|
SC Toulon | 26 | 7 | 10 | 9 | 26:26 | 0 | 31 |
| 12 |
|
AS Saint-Priest | 26 | 8 | 5 | 13 | 29:36 | -7 | 29 |
| 13 |
|
GFA Rumilly Vallières | 26 | 7 | 7 | 12 | 21:32 | -11 | 28 |
| 14 |
|
Lyon-La Duchère | 26 | 6 | 9 | 11 | 28:37 | -9 | 27 |
| 15 |
|
AS Monaco (CFA) | 26 | 6 | 8 | 12 | 25:38 | -13 | 26 |
| 16 |
|
Olympique Marseille (CFA) | 26 | 5 | 3 | 18 | 23:51 | -28 | 18 |
| Promotie | |
| Degradatie |
