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| 05.11.2021 | 20:00 | Angoulême CFC | - | FC Nantes (CFA) | 1:1 (1:0) | |
| 06.11.2021 | 18:00 | AS Béziers | - | FC Chamalières | 1:2 (1:0) | |
| 18:00 | Bourges Foot 18 | - | Vendée Les Herbiers | 1:1 (1:1) | ||
| 18:00 | Canet Roussillon | - | Bergerac Foot | 0:3 (0:2) | ||
| 18:00 | Le Puy Foot 43 | - | Angers SCO II | 1:0 (0:0) | ||
| 18:00 | Trélissac FC | - | US Colomiers | 0:0 (0:0) | ||
| 18:30 | Moulins Yzeure Foot | - | Andrézieux-Bouthéon FC | 2:1 (2:1) | ||
| 18:30 | Stade Montois | - | Montpellier HSC (CFA) | 1:2 (1:1) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Bergerac Foot | 11 | 6 | 3 | 2 | 17:8 | 9 | 21 |
| 2 |
|
Angoulême CFC | 11 | 6 | 3 | 2 | 18:12 | 6 | 21 |
| 3 |
|
Moulins Yzeure Foot | 11 | 5 | 4 | 2 | 10:7 | 3 | 19 |
| 4 |
|
Le Puy Foot 43 | 11 | 5 | 3 | 3 | 13:8 | 5 | 18 |
| 5 |
|
FC Nantes (CFA) | 11 | 4 | 5 | 2 | 14:11 | 3 | 17 |
| 6 |
|
Trélissac FC | 11 | 5 | 2 | 4 | 10:10 | 0 | 17 |
| 7 |
|
Andrézieux-Bouthéon FC | 11 | 5 | 1 | 5 | 14:11 | 3 | 16 |
| 8 |
|
Bourges Foot 18 | 11 | 4 | 3 | 4 | 12:8 | 4 | 15 |
| 9 |
|
AS Béziers | 11 | 4 | 3 | 4 | 10:12 | -2 | 15 |
| 10 |
|
Vendée Les Herbiers | 11 | 3 | 5 | 3 | 13:14 | -1 | 14 |
| 11 |
|
US Colomiers | 11 | 3 | 4 | 4 | 10:11 | -1 | 13 |
| 12 |
|
Angers SCO II | 11 | 3 | 3 | 5 | 10:13 | -3 | 12 |
| 13 |
|
Montpellier HSC (CFA) | 11 | 3 | 2 | 6 | 12:14 | -2 | 11 |
| 14 |
|
FC Chamalières | 11 | 3 | 2 | 6 | 13:18 | -5 | 11 |
| 15 |
|
Canet Roussillon | 11 | 6 | 3 | 2 | 13:11 | 2 | 10 |
| 16 |
|
Stade Montois | 11 | 0 | 0 | 11 | 8:29 | -21 | 0 |
| Promotie | |
| Degradatie |
