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| 29.04.2022 | 19:00 | Vendée Les Herbiers | - | Angers SCO II | 1:1 (1:0) | |
| 19:30 | Bergerac Foot | - | Angoulême CFC | 0:1 (0:1) | ||
| 30.04.2022 | 18:00 | Andrézieux-Bouthéon FC | - | Stade Montois | 3:3 (0:1) | |
| 18:00 | Canet Roussillon | - | Trélissac FC | 1:2 (0:1) | ||
| 18:00 | FC Nantes (CFA) | - | Moulins Yzeure Foot | 0:1 (0:1) | ||
| 18:00 | Montpellier HSC (CFA) | - | Le Puy Foot 43 | 1:3 (0:1) | ||
| 18:00 | US Colomiers | - | AS Béziers | 1:3 (1:2) | ||
| 18:00 | FC Chamalières | - | Bourges Foot 18 | 0:3 (0:1) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Bergerac Foot | 27 | 15 | 8 | 4 | 31:14 | 17 | 53 |
| 2 |
|
Le Puy Foot 43 | 27 | 15 | 7 | 5 | 36:16 | 20 | 52 |
| 3 |
|
Andrézieux-Bouthéon FC | 27 | 14 | 6 | 7 | 39:26 | 13 | 48 |
| 4 |
|
Bourges Foot 18 | 27 | 14 | 5 | 8 | 39:23 | 16 | 47 |
| 5 |
|
Angoulême CFC | 27 | 13 | 8 | 6 | 31:21 | 10 | 47 |
| 6 |
|
AS Béziers | 27 | 11 | 8 | 8 | 37:29 | 8 | 41 |
| 7 |
|
Moulins Yzeure Foot | 27 | 10 | 10 | 7 | 28:25 | 3 | 40 |
| 8 |
|
Vendée Les Herbiers | 27 | 9 | 8 | 10 | 29:31 | -2 | 35 |
| 9 |
|
Trélissac FC | 27 | 9 | 7 | 11 | 25:25 | 0 | 34 |
| 10 |
|
FC Nantes (CFA) | 27 | 8 | 9 | 10 | 28:29 | -1 | 33 |
| 11 |
|
Angers SCO II | 27 | 6 | 12 | 9 | 24:27 | -3 | 30 |
| 12 |
|
Canet Roussillon | 27 | 12 | 5 | 10 | 27:32 | -5 | 30 |
| 13 |
|
FC Chamalières | 27 | 7 | 7 | 13 | 28:39 | -11 | 28 |
| 14 |
|
Montpellier HSC (CFA) | 27 | 7 | 6 | 14 | 31:41 | -10 | 27 |
| 15 |
|
US Colomiers | 27 | 5 | 9 | 13 | 27:40 | -13 | 24 |
| 16 |
|
Stade Montois | 27 | 1 | 5 | 21 | 20:62 | -42 | 8 |
| Promotie | |
| Degradatie |
