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| 31.08.2018 | 23:00 | Cruz Azul Hidalgo | - | Sporting Canamy | 2:0 (2:0) | |
| 01.09.2018 | 02:30 | Dorados UACH | - | Tecos Fútbol Club | 2:1 (2:1) | |
| 02:30 | Atlético Reynosa | - | Pacific F. C. | 0:1 (0:1) | ||
| 03:00 | Coras de Nayarit | - | Loros UCOL | 0:0 (0:0) | ||
| 03:00 | Murciélagos FC | - | Correcaminos UAT II | 2:2 (2:2) | ||
| 17:00 | Cimarrones de Sonora II | - | Gavilanes de Matamoros | 1:1 (1:1) | ||
| 18:00 | Coyotes de Tlaxcala | - | Inter Playa | 1:1 (1:1) | ||
| 19:00 | Deportivo Toluca II | - | Pumas UNAM II | 3:2 (3:2) | ||
| 23:00 | Albinegros Orizaba | - | Tuxtla FC | 0:1 (0:1) | ||
| 23:00 | Real Zamora | - | Cocodrilos de Tabasco | 3:2 (3:2) | ||
| 02.09.2018 | 00:00 | Pioneros de Cancún | - | CF América II | 2:2 (2:2) | |
| 00:00 | Yalmakan FC | - | Tuzos de la UAZ | 1:1 (1:1) | ||
| 00:00 | Tepatitlán | - | Leones Negros II | 2:0 (2:0) | ||
| 17:00 | Deportivo Guadalajara II | - | Alacranes de Durango | 2:0 (2:0) | ||
| 18:00 | Club Necaxa II | - | Monarcas Morelia II | 1:1 (1:1) | ||
| 23:00 | Reboceros de La Piedad | - | Club Irapuato | 2:3 (2:3) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Club Irapuato | 2 | 2 | 0 | 0 | 6:2 | 4 | 10 |
| 2 |
|
Cruz Azul Hidalgo | 2 | 2 | 0 | 0 | 5:1 | 4 | 10 |
| 3 |
|
Loros UCOL | 2 | 1 | 1 | 0 | 5:2 | 3 | 10 |
| 4 |
|
Deportivo Toluca II | 2 | 2 | 0 | 0 | 7:3 | 4 | 8 |
| 5 |
|
Deportivo Guadalajara II | 2 | 1 | 1 | 0 | 4:2 | 2 | 8 |
| 6 |
|
Tuxtla FC | 2 | 2 | 0 | 0 | 3:1 | 2 | 8 |
| 7 |
|
Dorados UACH | 2 | 1 | 0 | 1 | 4:6 | -2 | 7 |
| 8 |
|
Pioneros de Cancún | 2 | 1 | 1 | 0 | 5:3 | 2 | 6 |
| 9 |
|
Tepatitlán | 2 | 1 | 1 | 0 | 4:2 | 2 | 6 |
| 10 |
|
Pumas UNAM II | 2 | 1 | 0 | 1 | 4:3 | 1 | 6 |
| 11 |
|
Gavilanes de Matamoros | 2 | 1 | 1 | 0 | 3:2 | 1 | 6 |
|
Pacific F. C. | 2 | 1 | 1 | 0 | 3:2 | 1 | 6 | |
| 13 |
|
Tecos Fútbol Club | 2 | 0 | 1 | 1 | 3:4 | -1 | 6 |
| 14 |
|
Monarcas Morelia II | 2 | 1 | 1 | 0 | 7:1 | 6 | 5 |
| 15 |
|
Correcaminos UAT II | 2 | 0 | 2 | 0 | 3:3 | 0 | 5 |
| 16 |
|
Real Zamora | 2 | 1 | 0 | 1 | 4:5 | -1 | 5 |
| 17 |
|
Reboceros de La Piedad | 2 | 0 | 1 | 1 | 2:3 | -1 | 5 |
| 18 |
|
Atlético Reynosa | 2 | 0 | 1 | 1 | 1:2 | -1 | 5 |
| 19 |
|
Leones Negros II | 2 | 1 | 0 | 1 | 3:2 | 1 | 4 |
| 20 |
|
Coras de Nayarit | 2 | 0 | 2 | 0 | 2:2 | 0 | 4 |
| 21 |
|
Tuzos de la UAZ | 2 | 0 | 2 | 0 | 1:1 | 0 | 4 |
| 22 |
|
Murciélagos FC | 2 | 0 | 1 | 1 | 3:4 | -1 | 4 |
| 23 |
|
Sporting Canamy | 2 | 1 | 0 | 1 | 1:2 | -1 | 4 |
| 24 |
|
Club Necaxa II | 2 | 0 | 1 | 1 | 1:4 | -3 | 4 |
| 25 |
|
Yalmakan FC | 2 | 0 | 1 | 1 | 1:2 | -1 | 3 |
| 26 |
|
Cocodrilos de Tabasco | 2 | 0 | 0 | 2 | 3:5 | -2 | 3 |
| 27 |
|
Inter Playa | 2 | 0 | 1 | 1 | 2:4 | -2 | 3 |
| 28 |
|
CF América II | 2 | 0 | 1 | 1 | 3:6 | -3 | 3 |
| 29 |
|
Coyotes de Tlaxcala | 2 | 0 | 1 | 1 | 1:4 | -3 | 3 |
| 30 |
|
Alacranes de Durango | 2 | 0 | 1 | 1 | 2:4 | -2 | 2 |
| 31 |
|
Albinegros Orizaba | 2 | 0 | 0 | 2 | 0:3 | -3 | 1 |
| 32 |
|
Cimarrones de Sonora II | 2 | 0 | 1 | 1 | 1:7 | -6 | 1 |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Degradatie |
