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| 13.10.2018 | 16:00 | CD Veracruz | - | Club Tijuana | 3:0 (1:0) | |
| 16:00 | Gallos Blancos | - | Monarcas Morelia | 1:1 (0:1) | ||
| 16:00 | CF Monterrey | - | Atlas Guadalajara | 1:3 (1:0) | ||
| 17:00 | Lobos BUAP | - | Cruz Azul | 0:3 (0:1) | ||
| 17:00 | Pumas UNAM | - | CF Pachuca | 3:2 (2:2) | ||
| 17:00 | Santos Laguna | - | Club León | 2:3 (0:1) | ||
| 17:00 | Club Necaxa | - | UANL Tigres | 2:1 (0:0) | ||
| 18:00 | CF América | - | Deportivo Toluca | 0:3 (0:2) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| 1 | |||||||||
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CF Pachuca | 12 | 10 | 1 | 1 | 29:6 | 23 | 31 |
| 2 |
|
Cruz Azul | 12 | 8 | 1 | 3 | 22:11 | 11 | 25 |
| 3 |
|
Pumas UNAM | 11 | 7 | 2 | 2 | 19:9 | 10 | 23 |
| 4 |
|
Deportivo Toluca | 12 | 6 | 3 | 3 | 24:12 | 12 | 21 |
| 5 |
|
Club Tijuana | 11 | 5 | 1 | 5 | 19:16 | 3 | 16 |
| 6 |
|
CF América | 11 | 5 | 1 | 5 | 14:18 | -4 | 16 |
| 7 |
|
CD Veracruz | 12 | 1 | 5 | 6 | 11:23 | -12 | 8 |
| 8 |
|
Puebla FC | 11 | 2 | 1 | 8 | 8:24 | -16 | 7 |
| 9 |
|
Lobos BUAP | 12 | 0 | 1 | 11 | 3:30 | -27 | 1 |
| 2 | |||||||||
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Club León | 12 | 8 | 3 | 1 | 25:13 | 12 | 27 |
| 2 |
|
Atlas Guadalajara | 11 | 6 | 2 | 3 | 28:19 | 9 | 20 |
| 3 |
|
Deportivo Guadalajara | 11 | 6 | 2 | 3 | 19:10 | 9 | 20 |
| 4 |
|
UANL Tigres | 12 | 5 | 4 | 3 | 15:15 | 0 | 19 |
| 5 |
|
Monarcas Morelia | 11 | 4 | 4 | 3 | 16:12 | 4 | 16 |
| 6 |
|
CF Monterrey | 12 | 4 | 3 | 5 | 23:24 | -1 | 15 |
| 7 |
|
Club Necaxa | 11 | 3 | 2 | 6 | 9:22 | -13 | 11 |
| 8 |
|
Santos Laguna | 12 | 2 | 3 | 7 | 16:25 | -9 | 9 |
| 9 |
|
Gallos Blancos | 12 | 2 | 1 | 9 | 13:24 | -11 | 7 |
